Alpha-1 Antitrypsin Deficiency

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NCT05856331 (Recruiting)

Study of INBRX-101 Compared to Plasma-derived A1PI Therapy in Adults With AATD Emphysema (ELEVAATE).

 

Asthma

 

NCT03373045 (Active, Not Recruiting)

Observational Study of Characteristics, Treatment and Outcomes With Severe Asthma in the United States (CHRONICLE)

 

NCT04609878 (Active, Not Recruiting)

Study to Assess PT010 in Adult and Adolescent Participants With Inadequately Controlled Asthma (KALOS)

 

NCT06261957 (Recruiting)

A Study to Assess and Compare Safety and Tolerability of 3 Months Treatment With Salbutamol Administered Via MDI Containing Propellant HFA-152a or HFA-134a in Participants 12 Years of Age and Older With Asthma

 

NCT05329194 (Active, Not Recruiting)

Effectiveness and Safety Study of Tezepelumab in Adults & Adolescent Participants With Severe Asthma in the United States. (PASSAGE)

 

NCT04718389 (Active, Not Recruiting)

A Study of GSK3511294 (Depemokimab) Compared With Mepolizumab or Benralizumab in Participants With Severe Asthma With an Eosinophilic Phenotype.  (NIMBLE)

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Bronchiectasis

 

NCT06280391 (Recruiting)

A Randomized, Double-blind, Placebo-controlled, Parallel-group, Proof-of-Concept (PoC) Study to Assess the Efficacy, Safety and Tolerability of Itepekimab, in Participants With Non-cystic Fibrosis Bronchiectasis (ACT18018)

 

Chronic Cough

 

NCT05599191 (Recruiting)

A 52-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough (CALM-1).

 

NCT05660850 (Completed)

A Study To Evaluate The Efficacy, Safety, Pharmacokinetics, And Pharmacodynamic Effects Of GDC-6599 In Patients With Chronic Cough

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COPD

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NCT03893370 (Active, Not Recruiting)

RejuvenAir® System Trial for COPD With Chronic Bronchitis.  (SPRAY)

 

NCT05326412 (Active, Not Recruiting)

Mechanistic Study of the Effect of Itepekimab on Airway Inflammation in Patients With COPD.  (AERIFY 3)

 

NCT05595642 (Recruiting)

A Study to Evaluate Astegolimab in Participants With Chronic Obstructive Pulmonary Disease.  (ARNASA)

 

NCT04320342 (Recruiting)

A Study Comparing Efficacy, Safety and Tolerability of the Fixed Dose Triple Combination CHF 5993 With the Fixed Dose Dual Combination CHF 1535 in Subjects With COPD.  (TRITON)

 

NCT05166889 (Recruiting)

Efficacy and Safety of Tozorakimab in Symptomatic Chronic Obstructive Pulmonary Disease With a History of Exacerbations.  (OBERON)

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NCT04701983 (Active, Not Recruiting)

Study to Assess the Efficacy, Safety, and Tolerability of SAR440340/REGN3500/Itepekimab in Chronic Obstructive Pulmonary Disease (COPD).

(AERIFY-1)

 

NCT06283966 (Recruiting)

A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease.  (THARROS)

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NCT05742802 (Recruiting)

Long-term Efficacy and Safety of Tozorakimab in Participants With Chronic Obstructive Pulmonary Disease With a History of Exacerbations (PROSPERO).

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NCT04053634 (Active, Not Recruiting)

Efficacy and Safety of Benralizumab in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With a History of Frequent Exacerbations.  (RESOLUTE)

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Pulmonary Fibrosis

 

NCT06097260 (Recruiting)

Randomized, Double-blind Study of Efficacy and Safety of Bexotegrast (PLN-74809) for Idiopathic Pulmonary Fibrosis

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Lung Cancer

 

NCT06122077 (Recruiting)

Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening

 

NCT05987189 (Recruiting)

Diagnostic Performance of Small RNA Blood Test in Patients Undergoing Follow-up Imaging After Positive Low Dose CT Screening for Cancer of the Lung.  (BOSTON II)

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